GPCR:G蛋白偶联受体
G蛋白偶联受体(GPCR)是一类广泛存在于生物体中的重要膜蛋白受体,其英文全称“G Protein Coupled Receptors”在学术和医学领域常被简写为“GPCR”,以便于快速书写和高效交流。这类受体参与多种生理过程的信号转导,常见于细胞生物学、药理学及疾病研究等综合领域,具有广泛的生物学功能和重要的应用价值。
G Protein Coupled Receptors具体释义
G Protein Coupled Receptors的英文发音
例句
- Melanocortin-4 receptor ( MC4R ) is a member of the superfamily of G protein coupled receptors ( GPCRs ), and can affect body weight, energy homeostasis and food intake in human and mouse.
- 黑素皮质素受体4(melanocortin4receptor,MC4R)是G蛋白偶联受体(GPCR)(Gproteincoupledreceptors,GPCRs)超家族的一个成员,在人和鼠的体重、能量稳态和采食量的调控中具有重要作用。
- Metabotropic glutamate receptors ( mGluRs ) is a novel family of G protein coupled receptors. Each subtype shows different features in the aspects of molecular biology, neuropharmacology and distribution in the central nervous system.
- 代谢性谷氨酸受体是一个新的G蛋白相关受体家族,各类亚型在分子生物学特征、神经药理学特征和中枢神经系统分布方面有所不同。
- Guanine nucleotide binding proteins ( G proteins ), known as an important signal transduction molecular, can physiologically couple extracellular signals identified by G protein coupled receptors ( GPCRs ) to a series of intracellular effector to cause changes of gene transcription and protein's structure and function.
- G蛋白是一类重要的信号转导分子,其生理功能是将细胞膜受体所识别的各种细胞外信号同细胞内一系列效应分子偶联起来,引起核基因转录及蛋白质结构和功能的变化。
- LPA influences target cells mainly by activating special G protein coupled receptors. The signal transduction system of LPA includes several known signal cascades : activating G q to stimulate PLC;
- LPA主要通过G蛋白偶联受体(GPCR)影响靶细胞功能,其信号转导系统包括已知的几条信号通路:激活Gq从而激活磷脂酶C;
- LPA can be generated and released by activated platelets as a product of the blood clotting process. The biological functions of LPA are mainly mediated by activating special G protein coupled receptors. At least four G protein-mediated signaling pathways have been identified in the action of LPA.
- 它是在血栓形成初期,由于血小板被激活而产生、释放,它主要由G蛋白偶联受体(GPCR)通过至少四种G蛋白介导的信号转导途径发挥其生物学效应。
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