MMR:失配修复突变
“错配修复突变”(Mismatch Repair Mutation)通常缩写为MMR,这一术语在医学领域,尤其是在英国的临床与科研文献中被广泛采用。通过使用缩写MMR,专业人士能够更高效地进行记录、交流和文献引用。该术语主要描述DNA错配修复系统中发生的基因变异,与遗传性肿瘤等疾病的研究密切相关。
Mutation in Mismatch Repair具体释义
Mutation in Mismatch Repair的英文发音
例句
- Frequent Ki-ras Mutation in MSI-H Colorectal Cancer Deficient in DNA Mismatch Repair Genes
- DNA错配修复基因缺陷的MSI-H大肠癌频发Ki-ras基因点突变
- It is usually considered that abnormal ac - cumulation of gene mutation result in tumorigenesis, which includes the deletion of mismatch repair genes ( MMR ) and the mutation of tumor suppressor genes.
- 通常认为,基因突变异常累积会导致一些肿瘤的发生,其中包括错配修复系统缺陷和抑癌基因突变。
- For the past few years, some research discovered that genetic mutation of DNA repair gene resulted in functional depression and deprivation of DNA mismatch repair system, which caused instability of genetic material, its main appearance is microsatellite instability ( MSI ) that led to carcinogenesis.
- 近年来研究发现DNA修复基因突变引起DNA错配修复系统的功能降低或丧失,从而引起遗传物质不稳定,主要表现为微卫星不稳定性(Microsatelliteinstability,MSI),进而导致肿瘤的发生。
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