NCA:非竞争性拮抗剂
“非竞争性拮抗剂”(noncompetitive antagonist,常缩写为NCA)是医学与药理学中的重要术语,指一类能够不可逆或长时间阻断受体活性的拮抗剂,其作用不依赖于激动剂的浓度。该术语在英国及其他英语国家的医学文献和临床实践中广泛使用,缩写NCA便于快速记录与交流,有助于提升专业文档和学术讨论的效率。
noncompetitive antagonist具体释义
noncompetitive antagonist的英文发音
例句
- A noncompetitive antagonist(NCA) prevents the agonist from producing any effect at a given receptor site.
- 非竞争性拮抗剂(NCA)可阻止激动剂在特定受体部位产生任何效应。
- Ketamine is a NMDA receptor noncompetitive antagonist(NCA), which has been administered clinically to treat acute or chronic pain syndrome. A lot of study have been carried about its effect of preemptive analgesia, but we have different results.
- NMDA受体非竞争性拮抗剂(NCA)氯胺酮在临床已用于急慢性疼痛的治疗,关于其在超前镇痛的作用基础与临床作了大量研究,但结果并不一致;
- Objective To investigate the effects of magnesium sulfate, a noncompetitive antagonist(NCA) of glutamate receptor, in focal cerebral ischemic injury of rats.
- 目的研究非竞争性谷氨酸受体拮抗剂硫酸镁在大鼠局灶脑缺血中的作用。
- BACKGROUND : Ketamine is a kind of frequently used general venous anesthesia drug in clinic, and the medication in vein or epidural cavum has analgesic effect. It is N-methyl-D-aspartic acid ( NMDA ) receptor noncompetitive antagonist(NCA), which can inhibit toxic effect of excitatory amino acids.
- 背景:氯胺酮是临床常用的静脉全麻药,静脉或硬脊膜外腔用药都有镇痛作用,它是N-甲基-D-天冬氨酸受体非竞争性拮抗剂(NCA),可拮抗兴奋性氨基酸的毒性作用。
- It was obviously that Glu have toxicity to neurons at the 12th cultured day. Noncompetitive NMDA receptor antagonist, MK-801, could reduce ratio of neuron death and apoptosis induced by Glu.
- Glu对原代培养12天的海马神经元具有明显毒性作用,非竞争性N-甲基-D-门冬氨酸受体拮抗剂MK-801(10μM)可明显降低Glu诱导神经元死亡与凋亡。
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