TRMP:硫嘌呤甲基转移酶
硫嘌呤甲基转移酶(英文全称:thiopurine methyltransferase,简称TPMT)是一种在医学与生理学领域具有重要意义的酶。它参与人体内嘌呤类药物的代谢过程,其活性水平对药物剂量调控和个体化治疗具有关键影响。为了便于书写与交流,该酶的名称在专业文献和临床实践中经常被缩写为TPMT。
thiopurine methyltransferase具体释义
thiopurine methyltransferase的英文发音
例句
- Objective To investigate thiopurine methyltransferase(TRMP) ( TPMT ) activity distribution in Chinese Han and Yao population.
- 目的研究巯基嘌呤甲基转移酶(TPMT)活性在中国汉族和瑶族人群中的分布。
- OBJECTIVE To study the influence of thiopurine methyltransferase(TRMP) ( TPMT ) activity on the pharmacokinetics ( PK ) of 6-mercaptopurine, which is the intermediate metabolite of azathioprine.
- 目的通过对硫唑嘌呤中间代谢物6-巯基嘌呤(6-mercaptopurine,6-MP)药动学的研究,初步探讨巯嘌呤甲基转移酶(thiopurinemethyltransferase,TPMT)活性对6-MP药动学的影响。
- HPLC Determination and Diversity Analysis of Thiopurine Methyltransferase Activity in Human and Pig
- HPLC法间接测定人和猪红细胞硫嘌呤甲基转移酶(TRMP)活性及其差异分析
- Influence of Thiopurine Methyltransferase Activity on Pharmacokinetics of 6-mercaptopurine, Which is the Intermediate Metabolite of Azathioprine
- 巯嘌呤甲基转移酶活性对硫唑嘌呤中间代谢物6-巯基嘌呤药动学的影响
- Objective To evaluate the activity and genotype of thiopurine methyltransferase(TRMP) ( TPMT ) and the concentration of thioguanine nucleotides ( TGNs ) as parameters for individualizing mercaptopurine ( 6-MP ) therapy.
- 目的探讨巯基嘌呤甲基转移酶(TPMT)活性、基因型和硫鸟嘌呤核苷酸(TGNs)浓度检测对6巯基嘌呤(6MP)化疗个体化的意义。
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